Lublin, Poland

Modern Methods of Drug Design and Analysis

Nowoczesne metody projektowania i analizy leków

Table of contents

⇑Modern Methods of Drug Design and Analysis at KUL

Language: Polish Studies in Polish
Subject area: arts
University website: www.kul.pl/kul,21.html
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⇑Definitions and quotes

Analysis
Analysis is the process of breaking a complex topic or substance into smaller parts in order to gain a better understanding of it. The technique has been applied in the study of mathematics and logic since before Aristotle (384–322 B.C.), though analysis as a formal concept is a relatively recent development.
Design
Design is the creation of a plan or convention for the construction of an object, system or measurable human interaction (as in architectural blueprints, engineering drawings, business processes, circuit diagrams, and sewing patterns). Design has different connotations in different fields (see design disciplines below). In some cases, the direct construction of an object (as in pottery, engineering, management, coding, and graphic design) is also considered to use design thinking.
Drug
A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.
Drug Design
Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. In the most basic sense, drug design involves the design of molecules that are complementary in shape and charge to the biomolecular target with which they interact and therefore will bind to it. Drug design frequently but not necessarily relies on computer modeling techniques. This type of modeling is sometimes referred to as computer-aided drug design. Finally, drug design that relies on the knowledge of the three-dimensional structure of the biomolecular target is known as structure-based drug design. In addition to small molecules, biopharmaceuticals and especially therapeutic antibodies are an increasingly important class of drugs and computational methods for improving the affinity, selectivity, and stability of these protein-based therapeutics have also been developed.
Analysis
Philosophers hasten too much from the analytic to the synthetic method ; that is, they draw general conclusions from too small a number of particular observations and experiments.
Lord Bolingbroke, reported in Austin Allibone ed. Prose Quotations from Socrates to Macaulay. (1903), p. 34
Analysis
My work in the future must be devoted entirely to pure mathematics in its abstract meaning. I shall apply all my strength to bring more light into the tremendous obscurity which one unquestionably finds in analysis. It lacks so completely all plan and system that it is peculiar that so many can have studied it. The worst of it is, it has never been treated stringently. There are very few theorems in advanced analysis which have been demonstrated in a logically tenable manner. Everywhere one finds this miserable way of concluding from the special to the general, and it is extremely peculiar that such a procedure has led to so few of the so-called paradoxes. It is really interesting to seek the cause.
Niels Henrik Abel, Letter to Professor Christoffer Hansteen (1826) Oeuvres Complètes de N. H. Abel, mathematician, Nouvelle edition (1881) ed., Peter Ludwig Mejdell Sylow & Sophus Lie, Vol. 2, pp. 263-265, as quoted by Øystein Ore, Niels Henrik Abel: Mathematician Extraordinary (1957) p. 113.
Design
Good design looks right. It is simple (clear and uncomplicated). Good design is also elegant, and does not look contrived. A map should be aesthetically pleasing, thought provoking, and communicative
Arthur H. Robinson (1953) Elements of Cartography p. 318
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